Alpha-blockers are a frontline treatment for lower urinary tract symptoms by relaxing prostate and seminal vesicle smooth muscles.

“generally speaking the Frontline ways that we manage it would be with an alpha blocker so there are um that's a a a class of compounds that that are nowadays very very specific to prevent activation of um set of smooth muscles that are really isolated mostly in the prostate and somewhat in the seal vesicles”

“alucin is the one I usually go to but there's another uh you know third 3.5 generation medication called sopin rap AOW is what that's go goes by and then alusin goes by um uh I don't know alusin and sopin are the two newest medications that are third generation that result in less impact on sexual dysfunction specifically less impact on semen production but have really really outstanding uh uh efficacy in terms of relaxing the prostate and improving urinary symptoms”

“but the more modern Med more modern ones um really effectively treat specifically the so they're selective in that they relax those muscles without dropping blood pressure”

“generally speaking the front line ways that we manage it would be with an alpha blocker so there are um that's a a a class of compounds that are nowadays very very specific to prevent activation of um set of smooth muscles that are really isolated mostly in the prostate and somewhat in the seminal vesicles”

“and the newest generation of ones will actually be more are even selective to the smooth muscle within the prostate and not the seminal vesicles so the seal vesicles and the prostate kind of grow up right next to each other for example when you do a radical prostatectomy you take out both organs they're attached to each other this seminal vesicles dump into the prostatic urethra so the second generation Third Generation Um antimuscarinics or I'm sorry alpha blockers would paralyze or prevent contraction of the prosthetic smooth muscle right so you would have improved urinary symptoms but would also have de impede ejaculation they would they would impede ejac the kind of the first more targeted ones would because they would in fact paralyze both paralyze both the newest generation of um the newest classes of these uh of these medications really focus only on prostate and so the impact on volume of emiss of seino emission or or semen is actually much less impacted”