Pharmaceutical versions of drugs like cocaine, amphetamine, and methamphetamine are structurally and chemically very similar to those used to treat ADHD, with a similar net effect of increasing dopamine and norepinephrine/adrenaline.

“Well, the pharmaceutical versions of those are exactly what are used to treat ADHD and they're not exactly like cocaine or methamphetamine, but they are structurally and chemically very similar and their net effect in the brain and body is essentially the same, which is to increase dopamine primarily, but also to increase levels of a neuromodulator called epinephrin or norepinephrine also called noradrenaline and adrenaline those names are the same and to some extent to increase levels of serotonin in the brain and blood, but not so much serotonin, that's just kind of a small smidgen of effect, okay?”