The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
but notice that the females did not reach significance so in the in the first group they barely do and you can see that because the confidence interval runs from 0.55 to 0.92 and notice the error bar almost touches the line
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and that about half the studies of antict 4 did indeed find that the drug was less effective in women than men which I found interesting
the most plausible explanations fit into two categories the first are maybe there are differences in the immune response to the drug if you're a man or a woman the second uh comes down to dosing I should have said this at the outset but of course these drugs are not like a pill where it's like everybody gets you know 50 milligrams of this they're all dosed based on weight so this study is dosed I believe at 3 milligrams per kilogram and because most men are heavier than women men are getting a higher dose than women
this study is dosed I believe at 3 milligrams per kilogram and because most men are heavier than women men are getting a higher dose than women
notice that in females while there's a trend towards risk reduction and this is risk reduction for overall mortality
about half the studies of antict 4 did indeed find that the drug was less effective in women than men which I found interesting
these drugs are not like a pill where it's like everybody gets you know 50 milligrams of this they're all dosed based on weight so this study is dosed I believe at 3 milligrams per kilogram