Nicotine, whether from smoking, chewing, or other forms of use, can alter human physiology over the long term.

“even nicotine is used by people uh you know whether they're you know smoking tobacco or chewing tobacco or something evolutionary i mean people do all kind of snuffing it oh yeah absolutely you know i paint uh uh yeah all these things like they're uh they're used and i but i think you know long term they're going to change our physiology”