Andrew Huberman· PhD
So things like methamphetamine, things like cocaine are terrible because they really ramp up the dopamine system so much that people really can't achieve dopamine release through any other mechanisms.
Loading…
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
So things like methamphetamine, things like cocaine are terrible because they really ramp up the dopamine system so much that people really can't achieve dopamine release through any other mechanisms.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
One of the reasons why meth is so dangerous in terms of its addictive potential and its potential to induce psychotic episodes is first of all how much dopamine it releases again five times more than any of the other drugs that we've been talking about but also how fat past that Peak comes on it's a very fast onset and that's true whether or not people are snorting it without their taking it orally or especially if they inject it intravenously but meth because it increases dopamine so fast into such a great degree and then the the peak in dopamine comes down very fast as well and it drops below the Baseline levels of dopamine that were present initially
things like cocaine and amphetamine are disastrous for most people because they release so much dopamine and they create these closed Loops where people then only crave the particular thing cocaine amphetamine that leads to those massive amounts of dopamine release