Selective Androgen Receptor Modulators (SARMs) are designed to be more anabolic relative to androgenic than compounds like Primobolan and Anavar.

“So the same idea was kind of adopted for SARMs and they tweaked and modified anti-androgens actually to make these compounds that would interact with the androgen receptor in a way that was tissue specific and try and get like pure anabolic activity with almost no androgenic”

“because technically SARMs are actually even further if I was to give the most extreme anabolic relative to”

“so selective Androgen receptor modulators some people might be more familiar with serms which are you've talked about Clomid tamoxifen on this podcast before selective estrogen receptor modulator so these will interact in a tissue specific way with estrogen receptors in various areas of the body so you might have have a you know inhibition of estrogen receptor activity in the breast for somebody who has you know breast cancer for example versus you would have like Pro estrogen activity in other areas of the body like bone which is what makes the selective action of it desirable because you can actually sort of choose where you get the activity you want but also don't impact the health of other tissues and other areas of the body so the same idea was kind of adopted for sarms and they tweaked and modified anti androgens actually to make these compounds that would interact with the Androgen receptor in a way that was tissue specific and try and get like pure anabolic activity with almost no androgenic”

“so selective Androgen receptor modulators these were kind of designed some people might be more familiar with CMS which are you've talked about Clomid tamoxifen on this podcast before um selective estrogen receptor modulator so these will interact in a tissue specific way with estrogen receptors in various areas of the body so you might have a you know inhibition of estrogen receptor activity in the breast for somebody who has you know breast cancer for example um versus you would have like Pro estrogen activity in other areas of the body like bone which is what makes the selective action of it desirable because you can actually sort of choose where you get the activity you want but also don't impact the health of other tissues and other areas of the body so the same idea was kind of adopted for sarms and they tweaked and modified anti-androgens actually to make these compounds that would interact with the Androgen receptor in a way that was tissue specific and try and get like pure anabolic activity with almost no androgenic”