The invasiveness of a placebo intervention correlates with the magnitude of the placebo effect, with injections having a greater effect than capsules or tablets, and medical devices yielding the largest effects.

“what perhaps is even Wild ER is the more invasive a placebo intervention is the greater the placebo effect so capsules have a bigger effect than tablets I don't know if that's more invasive but I guess it looks more medicinal to have a capsule versus a tablet who knows why but that's what's been observed an injection of a placebo has a greater effect than a consumption of a capsule or a tablet of course and if people are placed into a medical device or machine especially in cases where one of their limbs or both of their limbs or even their whole body is placed into a device even though the device is doing absolutely nothing specifically to our biological system it is inert right a bunch of buttons and a bunch of noises and a bunch of humming as if something were happening but nothing is happening that directly relates to any one specific biological system except and now you know what I'm about to say except expectation of what the machine is doing well that has the greatest placebo effect of all”