Andrew Huberman· PhD
And the layer five neurons in particular, went into a particular rhythm of electrical activity, this one to three Hertz rhythm after mice or humans were administered ketamine or PCP.
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And the layer five neurons in particular, went into a particular rhythm of electrical activity, this one to three Hertz rhythm after mice or humans were administered ketamine or PCP.
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And what they discovered was that it changes the rhythm of cortical activity in certain layers of the cortex. The cortex is like a layered sandwich. The cortex of course, being the outside of the brain. And there was a particular rhythm a one to three hertz rhythm. One to three hertz just means a particular frequency of electrical activity. In this case, in these layer 5 neurons of Retrosplenial cortex.
Well, yeah, and Karl had a brilliant paper in nature where he, it was from rats to humans in one paper. And he showed that there's this rhythmic discharge in the retrosplenial region, that is triggered by ketamine. And the rats actually showed dissociative like behavior, in that they