The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Kappa opioid receptors also have analesic effects. And it was for a long time thought that targeting cappa opioid receptors was the holy grail of painkillers because you got the same pain relief as you would get with something like morphine or even more potent opioids but the animals didn't want to abuse it.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Kappa opioid receptors also have analesic effects. And it was for a long time thought that targeting cappa opioid receptors was the holy grail of painkillers because you got the same pain relief as you would get with something like morphine or even more potent opioids but the animals didn't want to abuse it. So they moved into human clinical trials and we learned something in psychiatry at the moment that kappa opioid receptors cause dysphoria instead of euphoria.