The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
is that dopaminergic component necessary for... Let's say, we know that the amygdala is less reactive under acute effects, and that may play a role in... There's less sort of control from the amygdala, in terms of one's experience of memory, so it may be part of this sort of reprocessing, this reconsolidation of these memories in a different way, where the amygdala is not like going crazy, saying, freak out, like fight or flight.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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What it seems to allow is a very fast relearning or new associations to be tacked on to the previously traumatic experience.
So those positive experiences are essentially primed to be written in and over the traumatic experience and because of the high levels of Serotonin in the system and probably oxytocin as well, there's a safety that's written into the situation that allows people to lean into perhaps narratives or components of narratives that they would otherwise be holding back from.
Why would this state of mind and body be potentially useful for the treatment of trauma? Well, indeed it is revealing itself to be useful for the treatment of trauma. Again, these are legal clinical trials where people are doing this and discovering this. What it seems to allow is a very fast relearning or new associations to be tacked on to the previously traumatic experience.
MDMA seems to be a compound that produces the right kind of subjective and neurochemical milieu in the brain that allows therapy to be that much more potent within a limited number of sessions
MDMA ecstasy is a unique compound in that it leads to big increases in brain levels of dopamine and serotonin simultaneously, and I realized that the neuromodulators, like dopamine and serotonin, often work in concert, not alone the way they're commonly described in the more general popular discussions. However, it is a unique compound, and it's different than the serotonergic compounds like LSD and psilocybin. And there are now data still emerging that it might be and in some cases can be useful for the treatment of trauma, PTSD, and similar things.
so you have less fear better witness better memory all in the context of being more available and open and connected to the process and the facilitator and life because that's what oxytocin does it's a hormone for connection and bonding as well as safety and security especially in the right set and setting with someone that you trust