Paul Saladino· MD
and another thing that the industry is doing which physicians are culpable and liable is that they are using what is called a relative risk reduction David diamond points it out beautifully which is that when you have a benefit of about a half a percent and reduction of myocardial infarction in 28,000 patients that's the absolute reduction I think it's ridiculous in other words if you say I want to use 28,000 patients treat them with an intervention and at the end of three years or five years show you a half a percent reduction in myocardial infarction I'd say that's a ridiculous question that you're insane ants asking and it's a study that's not worth doing but what the medical profession has taken is that taken that number and use the analogy that Malcolm Ken Drake does and and let's use that because he says like let's say I am a lottery expert and the chances of you winning the lottery is one in ten million and I changed that and say hey Paul I can double your chances of winning the lottery that's a hundred percent increase and you would say yeah here I'll give you 50 bucks although the lottery ticket is only ten bucks on the other hand the increase of a hundred percent is actually going from one in ten million to two in ten million just buy two tickets you will save money so the one to two is being translated in clinical trials as a hundred percent improvement and that's relative risk reduction