Bryan Johnson exhibited altered behavior for several days after ketamine administration, indicating a change in openness and reduced feeling of being trapped.

“So I went back to the office the next day and we were walking to another room for a different meeting and there was a big wall in between like probably like a 5ft wall like a pretty size of a wall and instead of walking around the office to get around it I thought why don't I just jump over the wall that makes much more sense. And so I just jumped over the wall and I didn't think about it and my co-workers were like Brian what are you doing? That is really odd. and I thought, "Oh, you're right. I guess that might be a little odd." But yeah, my behavior was definitely changed and I was open to different ideas and I wasn't as trapped. It felt really liberating.”