The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
I think the problem is when you just blanket activate all the CB1 receptors in the brain indiscriminately like you do when you consume cannabis with THC the resulting effect is the intoxicating State and it's probably because there's a lot of CB1 receptors in the cortex and those are going to be differentially regulated at different times by endoc canabo
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
so so you're changing all the networks simultaneously yeah so if you hit a whole bunch of networks simultaneously you're just going to change the way that information processing and perception occurs and I think as a consequence of that that's what produces the intoxicating State not that THC is like a you know a super duper version of an endoc canabo or that it's boosting endoc canabidol as opposed to a system that's very finely tuned to do very specific things at very specific times
whereas THC when you consume it orally or inhalation wise and it gets into your blood and into your brain — it's just blanket activation you're just carpet bombing the whole system indiscriminately