Finasteride blocking progesterone conversion to allopregnanolone is a problem because allopregnanolone is implicated in depression, anxiety, and cognition.

“the problem the biggest problem is when you blocked progesterone getting into its neurosteroid called alool loone why is that important because Alo pregnanolone has been implicated for depression anxiety cognition right so some of those neurosteroids are very important when it comes to depression anxiety depression and cognition right”

“we were taught in medical school that finasteride blocks the conversion from testosterone to dihydro testosterone and that's it that's all we were told but that is only one fraction of the story because each one of those steroids then goes into something called a neurosteroid right so F DHD goes into Ander and diol that's the neurosteroid then you multiply that by six so six steroids are blocked and those six steroids then have a decreased conversion into their neurosteroid sorry the six steroids are blocked because five Alpha reductase acts on more than one exactly steroid cortical uhe progesterone aldosterone uh you can look at there's a whole linear not just testosterone”