Ketamine administration can alter cognitive frameworks, leading to novel problem-solving approaches.

“Before I did ketamine and I guess I did this actually unknowingly in the office, we're walking to another room for a different meeting and there was a big wall in between and instead of walking around the office to get around it, I thought why don't I just jump over the wall? That makes much more sense. And so I just jumped over the wall and I didn't think about it and my co-workers were like, "Brian, what are you doing? That is really odd." And I thought, "Oh, you're right. I guess that might be a little odd."”