Andrew Huberman· PhD
They will take these inhibitors that prevent the breakdown of dopamine and other so-called catacholamines, which allow more dopamine to be in circulation.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
They will take these inhibitors that prevent the breakdown of dopamine and other so-called catacholamines, which allow more dopamine to be in circulation.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Other things like MAO inhibitors, Monoamine oxidase inhibitors, work a different way. They inhibit the enzyme. Anytime you hear ase in biology, it's very likely an enzyme which breaks things down. so MAO inhibitors prevent the breakdown, not the re-uptake, but the breakdown of neurotransmitter and therefore allow more neurotransmitter to be available in the synapse and influence the postsynaptic cell.