Progesterone can exert negative feedback on the hypothalamic-pituitary-gonadal axis and may possess anti-androgenic activity.

“if you are not on exogenous hormones it is it does have negative feedback so similarly to most people are very familiar with how estrogen has negative feedback to the hypothalamus pituitary TC axis and testosterone through Androgen receptors but what often goes overlooked is some of the other hormones like progesterone so progesterone isn't as potent of a negative feedback regulator that I've seen but it definitely is and it seems to maybe even have anti-androgenic activity as well”

“and if it does that through you know competitive inhibition or like I don't really know off the top of my head I don't recall how it does it but it does seem to produce anti-androgen like effects”