Approximately one-third of patients experience significant benefits from micronized progesterone, including improved sleep and reduced anxiety, while another third notice no effect, and the final third are highly sensitive and may experience adverse reactions.

“Because when we give someone micronized progesterone, I would say a third of the patients love it and guzzle it like it's candy and they're the happiest people in the world. Helps their sleep. It reduces anxiety. Oh my god. Changes their life. Oh, it's absolutely life-changing. A third of the patients are like, I don't really notice. It doesn't bother me. I've got no, you know, it's fine. Like if you tell me I need to take it off, you tell me I need to take it to protect my uterus. no problem. And then you've got a third of patients who are very sensitive, right? The progester and even within that third, it is extreme.”