David Sinclair· PhD
So the buckets are mTOR, which respond to low amounts of amino acids, particularly leucine, isoleucine, valine.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So the buckets are mTOR, which respond to low amounts of amino acids, particularly leucine, isoleucine, valine.
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So IGF-1 is also a growth factor that you do need as well. So it's one of those things where you don't have any IGF-1, well you're going to be in trouble. I mean, there's a lot of positive things about IGF-1, muscle growth, muscle repair, neuronal growth.