The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And in most of the clinical studies, it's been shown that the dosage of 25 to 30mg given-- or I should say, taken once or twice-- and we'll talk about the spacing of sessions a little bit later, taken once or twice is what's leading to the most pronounced therapeutic outcomes.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Because as you'll soon learn as well, there are clinical studies showing that just one psilocybin journey can improve mood in a long-standing way. But most clinical trials involve two dosages spaced in very precise ways from one another with appropriate follow up.
A new study found two doses of psilocybin treatment administered two weeks apart produced large decreases in depression severity that remained low up to 1-year after treatment.