High doses of psychedelics may produce improvements in depression and addiction lasting months to over a year.

“That said in the big picture I think all of the most interesting thing about psychedelics are the heroic doses. I mean the idea you can give something one, two, three times and you see improvements in depression months later and in addiction you know over a year later and with these you know people dealing with potentially terminal illness.”

“I know several people who feel they've benefited tremendously from doing clinical work meaning with a guide in safe setting etc on highdose psilocybin maybe only two or three times total and that's it. >> Mhm. >> For treatment of depression sometimes for alcohol issues and other issues. I'm not talking about micro doing they do a high dose to two two to five grams.”