Andrew Huberman· PhD
Typically it was 20 milligrams per kilogram of body weight. So it depends on body weight. Or 30 milligrams of psilocybin per 70 kilograms of body weight. They were given in capsule form.
Loading…
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Typically it was 20 milligrams per kilogram of body weight. So it depends on body weight. Or 30 milligrams of psilocybin per 70 kilograms of body weight. They were given in capsule form.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Most of our studies are looking at where we want a psychedelic effect during the 20 to 30 milligram range.
So as I mentioned earlier, there are now about a dozen or so excellent studies, clinical trials exploring the use of single or two session psilocybin treatment in that 25 to 30-milligram range, which seems to be the most effective dose for long-lasting relief from depression.
some of which have demonstrated that appropriate dosages of psilocybin can alleviate major depression in more than 67% of people that take the drug.
What's really striking about this study, is that there was a very significant improvement in mood, and affect, and relief from depressive symptoms in anywhere from 50 to 70% of the people that were subjects in the study who received the psilocybin treatment.
so they're um to avoid exploitation conditions because there has been some exploitation mainly in the MDMA trials but um and then followup that it's been somewhere between 60 and 70% of people who go into that sort of thing with major depression that hasn't been resolved by other approaches um get either significant relief or uh full remission after two full versions of what I just described at fairly high dosages.