We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
But I do want to put a big asterisks, a highlight in an underlying beneath the statement I'm about to make, which is that pharmacology of the serotonin system just as pharmacology of the dopamine system is very broadband. It's a shotgun approach. You're going to hit all the circuits of the brain that involve serotonin with microdosing psilocybin. Although it has some selectivity for the 5-HT2A receptor it can attach to other receptors as well and act there.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.