Bryan Johnson· Author
Estradiol levels increased by 200%, consistent with preliminary published evidence that peripheral 5HT2A activation increases cortisol by driving aromatase expression.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Estradiol levels increased by 200%, consistent with preliminary published evidence that peripheral 5HT2A activation increases cortisol by driving aromatase expression.
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Estradiol levels increased by 200%, consistent with preliminary published evidence that peripheral 5HT2A activation increases cortisol by driving aromatase expression.
Estradiol levels increased by 200%, consistent with preliminary published evidence that peripheral 5HT2A activation increases cortisol by driving aromatase expression.
The increase is within the normal male range and is generally positive, as estradiol provides anti-inflammatory, neuroprotective and cardiovascular protective effects.
Estradiol increased 3x (11.3 to 36 pg/ml). This may be due to peripheral activation of 5HT2A receptors stimulating aromatase activity, the enzyme that converts testosterone to estradiol.