Microdosing psychedelics at sub-perceptible doses may alter neural circuits without causing hallucinations or catharsis.

“But microdose, one definition is that it's a dose of typically a classic psychedelic like LSD or psilocybin that has some perceptible psychedelic effects. It doesn't put you into a noticeable altered state of consciousness that feels like you're tripping.”

“Well, in a way, that's a little bit of what microdosing seems to be designed to do. Like you said, take dosages that are below that perceptual or awareness of some effect threshold over a longer period of time in an attempt to ping the circuits or alter the circuits but not hallucinate. Not have a catharsis.”