Andrew Huberman· PhD
The factors often are growth factors. Um, GDF11 is is one of them that has been described. Growth and differentiation factor. There is you know IGF-1 actually also has been described to be in young blood is is higher.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The factors often are growth factors. Um, GDF11 is is one of them that has been described. Growth and differentiation factor. There is you know IGF-1 actually also has been described to be in young blood is is higher.
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But what Amy found in her lab was a certain factor called GDF11, that goes down as you age. And it appears that maybe there are factors that pull the GDF11 out of circulation, maybe there are antibodies made for them, the factors. And if you give GDF11 to older mice, it seems to have all the benefits that this blood exchange has, this young blood has.
And, you know, the idea that we can isolate that factor that makes the old mice young again, and just give that factor by itself is fascinating.