David Sinclair· PhD
e.g. resveratrol, quercetin & fisetin activate the Sirt1 defense enzyme against diseases & aging.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
e.g. resveratrol, quercetin & fisetin activate the Sirt1 defense enzyme against diseases & aging.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And when I looked into it, these polyphenols do remarkable things to the body. The one that got the most media attention, because it's in red wine is resveratrol, but there's piceatannol and there's fisetin and quercetin these are supplements that people are getting excited about only now, but when you look into it, they activate and inhibit pathways or proteins in the body that are known to be important for health and longevity.