David Sinclair· PhD
resveratrol without food is largely insoluble.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
resveratrol without food is largely insoluble.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And this is actually why you suggested that maybe some resveratrol studies that have shown that it doesn't work as well as other studies show, those studies may have involved people who were feeding mice resveratrol without that additional fat.
now residuals not a very potent molecule we've got things that are a thousand times more potent now but the other problem with resveratrol is that it's not very soluble and the blood levels both in mice and in humans doesn't get up very high unless you eat some fat so that Western diet we had much better absorption than this low-dose lean diet