Rhonda Patrick· PhD
Stuart seems to think disuse and some combination of other factors like vascular insulin resistance contribute to the anabolic resistance of old age.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Stuart seems to think disuse and some combination of other factors like vascular insulin resistance contribute to the anabolic resistance of old age.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
At the same time, I think, there's probably aspects to do with insulin resistance, and it doesn't need to be overt insulin resistance to the degree that you have type 2 diabetes, but maybe you have what we call vascular insulin resistance.
And the number one answer is to be as physically active as you can, and that maintains that vascular level sensitivity as you get older.