Disuse atrophy events, such as those following surgery, falls, or illness, can lead to catastrophic and often irreversible muscle loss, particularly in older adults.

“So they've actually hopped. You know, they've accelerated the loss that they have with aging to a fairly large degree.”

“So disuse atrophy is a problem and anything that you can do to slow disuse atrophy is hugely important. Hugely important”

“So disuse atrophy events happen. They happen because they're planned. So surgeries, when you undergoing any kind kind of surgery, you're going to have a period of time when you are not mobile. You are not using your muscles. And when you're not using your muscles, you lose them. You lose them. They atrophy. Um, this could happen because you fell, you had a fall. Uh, so you're not going to be mobile for a period of time while you're recovering. This could happen because you have the flu or some other respiratory disease, and you're not moving around, right? So, there's a lot of reasons why particularly older adults have disuse atrophy events, planned or not planned. And when they lose that muscle, it is catastrophic because they can never gain it back like they had before they lost it.”