Among centenarians, women in the lowest quartile of IGF-1 levels do not have a higher likelihood of sarcopenia but exhibit better cognitive function and tend to live longer.

“those women also have better cognitive function and as far as muscle function it's not different in other words they are not paying I think I think a lot of our problem when we come from sports right we're trying to preserve muscle and I'm not sure that low igf is the best way to preserve muscle I think maybe it's making the muscle a biology better but it's not making the muscle any better sorry just to be clear you're saying that the women in the bottom uh quartile say of igf are no more likely to be sarcopenic than the women with higher igf but they do tend to live and smarter and cognitively they have better cognitive function right”