Paul Saladino· MD
four hydroxy no no one of these reactive aldehyde products of linoleic acid metabolism appears to break the the division the sort of um the hyperplasia ability of adipocytes
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
four hydroxy no no one of these reactive aldehyde products of linoleic acid metabolism appears to break the the division the sort of um the hyperplasia ability of adipocytes
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how do you get big adipocytes you get lots of linoleic acid you get lots of 4-h and e again i'm going to have tucker on the podcast soon and your adipocytes will expand they will get hypertrophic versus hyperplastic hyperplastic is when you have lots of small adipocytes hypertrophic is when you have big adipocytes which spew out free fatty acids that is the root of the problem
and the breakdown products of lenic acid specifically hn 4 hne for hyd tox onol a molecule you'll be familiar with if you listen to my podcast with Tucker goodr is known to affect fat cells negatively