Animal models suggest linoleic acid can cause gut dysbiosis, and omega-3 fish oil may not attenuate this effect, potentially causing issues with lipopolysaccharide and endotoxemia.

“animal models suggest that linoleic acid could also be causing dysbiosis studies such as this one and animal models are what i would draw that conclusion from they're saying that omega-3 fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis so in these animal models they can induce dysbiosis and colitis with omega-6 polyunsaturated fats but it impairs lps dephosphorylation causing sepsis so using fish oil to treat omega-6 cause problems didn't result in good things in animal models”