Linoleic acid intake above 3-4% of the diet is associated with increased cancer rates.

“they showed that at one percent linoleic which is the ancestral there was no effect on carcinogenesis and on acceleration you know in tumor encrusted rats and they showed that two or three or four percent then you got an increase in cancers rate of growth and after three or four percent linoleic in the diet if you kept bringing it up to ten or twelve it didn't get worse so it was interesting there is if three or four percent is too much really and we have everyone at between six and 14 percent now you're not even going to see a signal in epidemiology between linoleic acid and cancer because everyone's above the threshold”