Paul Saladino· MD
your satiety mechanisms work unless you break them with excess linolic acid and linolic acid breakdown products to Ag and nandom which bind to the cv1 receptor in your brain
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
your satiety mechanisms work unless you break them with excess linolic acid and linolic acid breakdown products to Ag and nandom which bind to the cv1 receptor in your brain
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I would posit that it's probably related to linoleic acid breakdown products affecting satiety in the brain through the cannabinoid receptors
if you decrease your consumption of sea oils you decrease the formation of endocannabinoids in the gut and you are less hungry
another in a follow-up to that a study in mice showing the increased linoleic acid led to increased endocannabinoids which led to weight gain and increased hunger
and increased linoleic acid intake in our diet increases to Ag and aea which increases stimulation of CB1 and this has been shown you know very clearly in rodent studies
could it also be the fact that if we eat linoleic acid that linoleic acid could be turned into endogenous cannabinoids in our bodies something we know that happens and triggering CB1 receptors on mitochondria creating some degree of mitochondrial dysfunction
linoleic acid also turns into endogenous cannabinoids in the gut and can trigger CB1 receptor cannabinoid receptors in the gut leading to hunger feelings of lack of satiety and I think that leads to a lot of overeating that we're seeing in our culture today