The linoleic acid metabolite 'ona' induces arterial calcification in mice and appears to do so in humans, and also induces thromboxane production in plasma.

“ona is another common linoleic acid metabolite uh it induces arterial calcification in mice and it appears to do so in humans this is from a paper back in 2017 that hasn't been re produced yet um it also induces thromboxane production in plasma and is probably followed by the development of diseases such as thrombus formation and platelet aggregation so this could be you know an interesting you know why are people with cardiovascular disease so prone to clot formation well this is a mechanism that could explain it”