Carboxyl pyrol, a breakdown product of vegetable oils, can induce autoimmunity by forming antibodies that cross-react with retinal antigens.

“but with regard to carboxyl pyrol and um macular degeneration first of all I I don't know that this is a major player Paul but it is a player like I said and there's many many arrows all coming together you know with with regard to macro degeneration but with carboxyl pyrol we actually know that um this molecule is creating autoimmunity in some people and so so this breakdown product um called Rex ethylpyrol then can cause um sap we've shorten that this app separated antibodies and so those antibodies then can cross react with antigens in the retina and this may be part of macro degeneration”