Serum levels of linoleic acid are not a good indicator of long-term linoleic acid consumption or a predictor of adverse health events, unlike adipose tissue levels.

“there's tons of research that shows the more linoleic acid you consume the more linoleic acid ends up in your ldl particles which is your cholesterol quote unquote right and in your adipose tissue”

“serum levels of linoleic acid probably are not a great indicator long term of overall linoleic acid consumption presumably because some of that linoleic acid can become oxidized into the oxy lipids which we're going to talk about a little bit in this podcast i talked about it previously with tucker goodrich on this podcast but if linoleic acid gets oxidized into 4h and e 9 and 13 hold then then you're going to see less linoleic acid in the blood and so serum or plasma levels of linoleic acid are probably not good correlates for chronic illness serum levels are probably just not not good correlates for consumption but adipose tissue levels are”

“but if you look at adipose tissue levels those actually do correlate with coronary artery disease in a small study of 226 people”

“we can look at the adipose tissue of humans and tell how much linoleic acid they've been eating because the adipose tissue stores linoleic acid it's stores it's a history book you can get rid of it when you decrease your linoleic acid gradually”

“unfortunately plasma levels of linoleic acid are not always an accurate representation of the dietary consumption of linoleic acid so we need to look at subcutaneous adipose tissue levels of fatty acids to really get a sense of linoleic acid”

“they say that our results indicate that adipose tissue so fatty acids in the adipose tissue linoleic acid has increased by 136 percent in the adipose tissue over the last half century this increase is highly correlated with an increase in dietary linoleic acid increase over the same time”

“I think that adipose linoleic acid is a better metric of consumption but it's difficult to assay that it's a much it's a metric of long-term consumption absolutely”

“in fact the only seriously good metric that will reflect linoleic acid consumption in diet is adipose tissue with an oleic acid I know there was a large study that you posted on Twitter looking at linoleic acid in the human diet and cardiovascular disease and I can show that study if you want I have the reference unfortunately if you look at that study of all the studies they looked at only one or two maybe three Macs looked at adipose issues with linoleic acid and in in none of those studies was there any significant association between adipose linoleic acid and improved cardiovascular outcomes meaning more linoleic acid improved cardiovascular outcomes and there are studies that show increased linoleic acid in the adipose tissue and worse cardiovascular outcomes”

“in none of those studies was there any significant association between adipose linoleic acid and improved cardiovascular outcomes meaning more linoleic acid improved cardiovascular outcomes and there are studies that show increased linoleic acid in the adipose tissue and worse cardiovascular outcomes”

“the only seriously good metric that will reflect linoleic acid consumption of diet is adipose tissue with an oleic acid”