In REM sleep serotonin is essentially absent. Okay? So this molecule, this neuromodulator that tends to create the feeling of bliss and wellbeing and just calm placidity is absent. All right. So that's interesting. In addition to that, norepinephrine this molecule that's involved in movement and alertness is absolutely absent. It's probably one of the few times in our life that epinephrin is essentially at zero activity within our system.