Paul Saladino· MD
if you do an NMR if you do a nuclear magnetic resonance lipid profile you can get the Nana mole per liter of Cove lvl and you can get the Nana mole per liter and that will give you a number because molar measurements are numbers of particles I can get a particle number for LDL in my body and if you calculate the number of particles LDL particles in someone's body who has an LDL of 70 milligrams per deciliter which you know 99% of cardiologists in this country would say that's fantastic that number is still astronomically large like ten to the sixteenth ten to the sixteenth particles of LDL floating around in your bloodstream in my bloodstream when we have an LDL of 70 milligrams per deciliter but if you go to your cardiologist and you have an LDL of 150 milligrams per deciliter and that number is now twice as big instead of one times ten to the sixteenth it's two times ten to the 16th that amount of LDL particles is going to kill you if you just do sort of the Brownian motion chaotic physics of it all 10 to the 16th particles is a massive number of LDL particles in fact it's larger than the number of cells in our body and that number of LDL particles will not lead to atherosclerosis but two times in the sixteenth that will lead to atherosclerosis and it's just that never makes sense to me and not taken on the account that like what are we doing here that's that can't be the issue the whole paradigm of lowering LDL makes no sense to me there has to be something else going on this spark to light the fire which people who listen to my podcast will know that I believe is insulin resistance and we can talk to him about that but have you ever thought about that in terms of the calculation and the actual number of LDL particles in the human body even when it's astronomically low even if you do something like the Ferdie a trial where you give someone a statin and a one of these monoclonal antibody you know antibodies that really really lower pcsk9 inhibitors you can get the LDL into the 40s and 50s people still have large amounts of part of axé