Rhonda Patrick· PhD
if you have obviously if you've been doing resistance training uh up until that point and continuing it you're building not only bone you you know certainly built up a lot of bone density Reserve earlier in life but muscle mass helps right and then let me throw this at you um because I've you know I've thought a lot about the nuclear hormone nuclear hormones basically like so so vitamin D is the one that I've really focused on and when I was doing a lot of research on it so so nuclear hormones you know we have steroid hormones nuclear steroid hormones I should say sorry so we have estrogen testosterone vitamin D is one so these are these are binding to a receptor that you know in some cases the receptor complexes with other ones it goes into the nucleus of a cell which is where all the DNA is and it goes down to the level of genes and it regul recognizes a little sequence of genes so in the case of estrogen it's called an estrogen response element and ER in the case of vitamin D is called a vdre a vitamin D response element um there's a lot of overlap between vitamin D and the estrogen in terms of the genes they're regulating and so I'm wondering if avoiding vitamin D deficiency also becomes one of those important lifestyle factors because uh you know in some cases obviously vitamin D also plays a own role in bone metabolism right but independent of that also just looking at the cross Talk of the genes that vitamin D and estrogen regulate and they're like they're both and the the the response elements are they're different but there's somewhat I'm looking at that it's like oh I wonder if there's like that seems like you might be able to compensate a little so it's kind of another interesting in addition to being you know Physically Active resistance training one of the most important things right um but also like I did a lot of jump roping I was like Star jump roper as a kid lots and lots of jumping rope which there is evidence that that also builds bone Den