Rhonda Patrick· PhD
Sulforaphane, which is high in broccoli sprouts, clears away brain amyloid plaques and tau tangles and ameliorated memory defects in mice engineered to get Alzheimer's disease.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Sulforaphane, which is high in broccoli sprouts, clears away brain amyloid plaques and tau tangles and ameliorated memory defects in mice engineered to get Alzheimer's disease.
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Injection of our favorite NRF2 activator sulfurophane has been shown to improve spatial working memory and short-term memory in mice injected with amalloid beta aggregates in order to cause a disease similar to Alzheimer's disease.
As one of the most potent inducers of the cellular antioxidant and anti-inflammatory network through its robust activation of NRF2, it probably shouldn't surprise us that it has been shown to prevent the death of neurons and improve pathologies associated with neurogenic diseases in the brains of animals.