The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
I do supplement with something called alpha-GPC, which is, essentially, in the acetylcholine pathway, or biosynthesis pathway. I don't take it very often, but I will take 300 milligrams of alpha-GPC from time to time. From time to time, I mean anywhere from two to three times per week. I'll generally do it early in the day, 'cause it, for me, can have a little bit of a stimulant effect.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
So my particular protocol, the one I use is I'll take phenylethylamine at dosages of about 300 to 600 milligrams along with some L-tyrosine, or I'll take it on its own with a molecule, or I should say a compound that we'll talk about a little bit later as it relates to acetylcholine, Alpha-GPC, but tyrosine and phenylethylamine taken alone or together will make you feel more motivated and more alert, more willing and able to lean into particular motivated behaviors, whether or not they're physical or cognitive.
I would use Alpha-GPC by taking it about 10 to 20 minutes prior to any time I want to focus or concentrate very deeply. I've taken as much as 600 milligrams at one time, although I find that 300 milligrams is enough for me
I rely on something else for dopamine augmentation which is phenylethylamine which is a little bit more short lasting