Andrew Huberman· PhD
Nic increases the amount of dopamine about 150% above Baseline
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Nic increases the amount of dopamine about 150% above Baseline
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Nicotine, in particular, nicotine that is smoked, like cigarettes and so forth, increases dopamine two and a half times above baseline. It is very short-lived.