Andrew Huberman· PhD
Testosterone improves glycemic control. Testosterone improves insulin signaling.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Testosterone improves glycemic control. Testosterone improves insulin signaling.
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I think there's, two years ago, was it two years ago or maybe a year ago, very good study came out that looked at pre-diabetic men, you've probably talked about this study, and looking at insulin resistance and glucose disposal with and without testosterone.
you can show the causal effect of testosterone by giving synthetic testosterone and testosterone replacement therapy so for instance when they give diabetic men who have low testosterone when they give them testosterone replacement their insulin sensitivity is like is at least in part restored you know they're fasting glucose fasting insulin comes down — hba1 hp 1ac things of that nature
we know from clinical trials that when you give a group of insulin resistant men testosterone their insulin resistance improves we know that if you give men testosterone and you provide them with a training stimulus muscle mass increases strength increases body composition improves which means adipose tissue goes down we know that mood improves
There's certainly evidence that insulin resistance can be ameliorated by um by correcting hypogonatism.
There's certainly evidence that insulin resistance can be ameliorated by um by correcting hypogonatism.