Progressively reducing nicotine dosage while telling the user it's the same amount could be a strategy for quitting nicotine.

“if somebody were trying to quit nicotine for instance and they were going to do that by progressively reducing the amount of nicotine that they were taking but you told them that it was the same amount one from one day to the next you could Whittle it down to presumably to a low amount before taking it to zero and if they believed it to be a greater amount then it might actually not uh disrupt their reward Pathways meaning they would feel um presumably they'd feel rewarded by whatever nicotine they were bringing in”