Food reward systems in individuals with type 2 diabetes or other metabolic disorders can be rewired.

“food preference, and the ability to reshape these circuits is not disrupted in these people to the point where it can't be rewired, and that's very encouraging, because what it means is that, for people that are suffering from these syndromes, through some simple alterations in dietary choice, provided those are carried out over time and in the correct way, by pairing with the foods that will appropriately shift metabolism of the brain, one can actually rewire what they consider not just palatable, but attractive as foods.”