Paul Saladino· MD
the one that's circled in red is what happens to a mitochondria when used damaged cardiolipin through in this case excessive seed oil feeding and then combined with hypo or hyperglycemia it causes the mitochondria to collapse and basically to stop being able to function which as one can imagine given how we've discussed how mitochondria and therefore cardiolipin are fundamental to life is a bit of a problem right what this causes in the little chart b here that little circle is what happens to a mitochondria ability to burn glucose after you've fed it seed oils and then induced hyperglycemia basically complex one collapses and fails and it's unable to burn substrates which in this model this mouse study because it exhibits exactly what i'm trying to describe is what happens in humans as they get older they develop an inability to burn glucose and a preference for an ironic preference for fatty acids because their mitochondria are so damaged which leads you to heart failure which is what they are inducing in these mice in a few days through seed oil feeding and hyperglycemia