The antibody associated with autoimmune central B12 deficiency is present in approximately 6% of healthy individuals, 20% of those with lupus and neuropsychiatric symptoms, and about 50% of individuals with demyelinating conditions of unknown etiology.

“they sampled just a general healthy control and about 6% of those people have this antibody wow it's really high they then sampled people with neuros psychiatric lupus so these are people who have an autoimmune disorder already lupus and they have neuros psychiatric symptoms 20% of them had this antibody and then they just recently this is unpublished data but they have looked at people who have a demyelinating condition of unknown iology and about 50% of them had this anti 5% so this is like an MS like condition had this antibody”