More info on Berberine (BBR). This data is from an article we co-published in 2012 on fat

Well SupportedGut microbiota metabolize carnitine and choline into trimethylamine, which the liver converts to trimethylamine oxide (TMAO).

Partially SupportedBerberine inhibits the production of TMAO, similar to how it lowers blood sugar like metformin.

Partially SupportedLook for 'GMP' certification and verify the yellow solid appearance when purchasing berberine supplements.

Partially SupportedBerberine at 100 mg/kg/day in rats increased mitochondrial activity and reduced fat and glucose levels.

Partially Supported